List of PARP inhibitors (Poly (ADP-ribose) polymerase ... - Drugs.com
2023年4月14日 · Poly (ADP-ribose) polymerase inhibitors, also called PARP inhibitors, are targeted therapies that are used to treat cancer. PARP is a protein that has a role in cellular growth, regulation, and cell repair and it helps cancer cells repair themselves and survive.
PARP inhibitor - Wikipedia
PARP inhibitors are a group of pharmacological inhibitors of the enzyme poly ADP ribose polymerase (PARP). They are developed for multiple indications, including the treatment of heritable cancers. [1] Several forms of cancer are more dependent on PARP than regular cells, making PARP (PARP1, PARP2 etc.) an attractive target for cancer therapy.
What are PARP inhibitors? - MD Anderson Cancer Center
2024年4月3日 · PARP inhibitors are a type of targeted therapy commonly used to treat breast cancer and ovarian cancer, among others. They target PARP, or poly (ADP-ribose) polymerase, which is a protein in cells that helps repair damaged DNA.
What is a PARP inhibitor? Uses, how they work, and options
2021年3月15日 · PARP inhibitors are drugs that prevent cancer cells from repairing, allowing them to die. Here, learn when doctors prescribe them and more.
List of PARP inhibitors: Uses, common brands, and safety …
2022年4月7日 · PARP inhibitors are a class of drugs used for cancer treatment known as a type of targeted cancer therapy. Targeted cancer therapies are drugs that block the growth and spread of cancer. Targeted therapies do this by interfering with …
PARP Inhibitor: Targeted Therapy Drugs for Cancer
2022年1月12日 · PARP inhibitors are drugs that block the DNA-repairing mechanism of PARP. By preventing PARP from repairing the damaged DNA within cancer cells, PARP inhibitors can help kill them.
PARP Inhibitors | Targeted cancer drugs | Cancer Research UK
2024年9月24日 · PARP inhibitors are a type of targeted cancer drug. They are a treatment for several types of cancer including ovarian, breast and prostate cancer. They are also in trials as a treatment for other types of cancer.
Poly (ADP-ribose) polymerase (PARP) inhibitors - DrugBank Online
A poly (ADP-ribose) polymerase (PARP) inhibitor used to treat recurrent ovarian and prostate cancers in previously treated adults.
How Do PARP Inhibitors Work? Uses, Side Effects, Drug Names - RxList
PARP inhibitors are a group of pharmacological inhibitors of the enzymes, PARP-1 and PARP-2, which play an essential role in DNA repair.
PARP and PARG inhibitors in cancer treatment - PMC
Four PARP inhibitors, olaparib, rucaparib, niraparib, and talazoparib, have been approved by the U.S. Food and Drug Administration (FDA) and by the European Medicines Agency (EMA).