10% Body weight (gain) change as criterion for the maximum …
2022年10月1日 · Using the 10% lower weight gain criterion and incorrectly associating it with excessive toxicity has major implications for top dose selection in regulatory safety studies, resulting in tests performed at doses too low to elicit toxicity.
10% Body weight (gain) change as criterion for the maximum
Using the 10% lower weight gain criterion and incorrectly associating it with excessive toxicity has major implications for top dose selection in regulatory safety studies, resulting in tests performed at doses too low to elicit toxicity.
Body mass index, weight change, and cancer prognosis: a meta …
We aimed to assess the strength and validity of the evidence of the association between BMI or weight change and cancer prognosis by a systematic evaluation and meta-analysis of relevant cohort studies.
The multifactorial effect of obesity on the effectiveness and …
2024年9月23日 · Epidemiology studies have demonstrated a clear association between obesity and the development of several distinct malignancies, with excessive visceral adiposity being an increasingly prevalent...
Adult weight gain and adiposity-related cancers: a dose-response meta …
2015年3月10日 · The relative risk of kidney cancer comparing highest and lowest level of adult weight gain was 1.42 (95% CI = 1.11 to 1.81). Adult weight gain was unrelated to cancers of the breast (premenopausal women, postmenopausal HRT …
Drugs Commonly Associated With Weight Change: A Systematic …
2015年2月1日 · To aid in the development of the Society guidelines, we conducted this systematic review and meta-analysis aimed at summarizing the evidence about commonly prescribed drugs and their associations with weight loss or weight gain.
Lithium toxicity profile: a systematic review and meta-analysis
Lithium was associated with an increased risk of reduced urinary concentrating ability, hypothyroidism, hyperparathyroidism and weight gain. There was little evidence for a clinically significant reduction in renal function.
Toxicity of chemotherapy dosing using actual body weight in …
2012年5月20日 · We performed a systematic review and meta-analysis to determine whether, among adults receiving chemotherapy dosed by actual body weight (ABW), obese patients experience differing toxicity or survival compared to normal-weight patients.
Food Groups and Risk of Overweight, Obesity, and Weight Gain: …
Therefore, we conducted a systematic review and meta-analysis to investigate the potential associations between 12 predefined food groups, including whole grains, refined grains, vegetables, fruit, nuts, legumes, eggs, dairy, fish, red meat, processed meat, and SSBs, and the risk of overweight/obesity, abdominal obesity, and weight gain, complet...
Food Groups and Risk of Overweight, Obesity, and Weight Gain: …
2019年3月1日 · This meta-analysis summarizes the evidence of a prospective association between the intake of foods [whole grains, refined grains, vegetables, fruit, nuts, legumes, eggs, dairy, fish, red meat, processed meat, and sugar-sweetened beverages (SSBs)] and risk of general overweight/obesity, abdominal obesity, and weight gain.