CDC42 - Wikipedia
Cell division control protein 42 homolog (Cdc42 or CDC42) is a protein that in humans is encoded by the CDC42 gene. Cdc42 is involved in regulation of the cell cycle.
CDC42 Gene - GeneCards | CDC42 Protein | CDC42 Antibody
2024年12月9日 · CDC42 (Cell Division Cycle 42) is a Protein Coding gene. Diseases associated with CDC42 include Takenouchi-Kosaki Syndrome and Nocarh Syndrome. Among its related pathways are Regulation of actin dynamics for phagocytic cup formation and GPCR Pathway.
细胞分裂周期蛋白42在肿瘤发生发展和治疗中作用的最新进展
Cdc42在多种恶性肿瘤中呈现高表达，并和肿瘤的发生、侵袭和转移密切相关，提示Cdc42可能为肿瘤治疗的潜在靶点。 该文拟从Cdc42的形态结构、功能、信号通路上下游效应分子以及在人类肿瘤侵袭和转移中的作用等方面进行综述。
CDC42 - 百度百科
该基因编码的蛋白质是Rho亚家族的小GTP酶，它调节控制多种细胞功能（包括细胞形态，迁移，内吞作用和细胞周期进程）的信号传导途径。 该蛋白质与 酿酒酵母 Cdc 42非常相似，并且能够补充酵母cdc42-1突变体。 据报道，致癌基因Dbl的产物特异性催化GDP从该蛋白 ...
Cdc42蛋白 - 百度百科
Cdc42蛋白，是一种癌细胞转移所需的关键蛋白，它能帮助癌细胞通过血液扩散到身体的其他部位。 以这种蛋白为靶点，或将成为预防继发性癌症（癌症转移）的有效方法。
Cdc42, a Rho GTPase and regulator of actin-based ... - Cytoskeleton
Cdc42 is a 21 kDa small GTPase, a member of the Ras super-family and Rho sub-family of GTPases, that upon activation by a guanine nucleotide exchange factor (GEF), is essential in regulating actin cytoskeletal re-arrangement as a part of a signal transduction pathway transducing extracellular signals (activation of cell surface receptors and ...
细胞分裂周期蛋白42 在肿瘤中的作用及其分子机制研究进展 …
细胞分裂周期蛋白42(cdc42)是小g蛋白rho家族的核心成员，在与gtp结合/活化状态和与gdp结合/失活状态之间循环切换，在复杂的细胞信号转导网络中，发挥开关作用，调控细胞的微丝骨架结构，与细胞的生长、迁移和黏附等重要生物学行为事件关系密切。
Cdc42: An Essential Rho-Type GTPase Controlling Eukaryotic Cell ...
A Drosophila homolog of the Rac- and Cdc42-activated serine/threonine kinase PAK is a potential focal adhesion and focal complex protein that colocalizes with dynamic actin structures. Mol. Cell.
Signaling Role of Cdc42 in Regulating Mammalian Physiology
C, Cdc42 coordinates the survival signal from the IL-7 receptor (IL7R) and the proliferative signal from the T cell receptor (TCR) in regulating naive T cell homeostasis. D, Cdc42 integrates M-CSF- and RANKL-induced osteoclastogenic signals to regulate osteoclast proliferation, survival, and bone resorption.
Regulating Cdc42 and Its Signaling Pathways in Cancer: Small
2018年3月29日 · In this review, we analyze the newly recognized regulation mechanisms for Cdc42 and Cdc42-related signal pathways, and particularly new treatments using small molecules and miRNAs to inhibit the abnormal overexpression of Cdc42 that may slow down the metastasis process, improve cancer therapy and lead to novel strategies for development of ...