Local anesthetic - Wikipedia
Many local anesthetics fall into two general chemical classes, amino esters (top) and amino amides (bottom). A local anesthetic (LA) is a medication that causes absence of all sensation (including pain) in a specific body part without loss of consciousness, [1] providing local anesthesia, as opposed to a general anesthetic, which eliminates all ...
Amide Local Anesthetics - LiverTox - NCBI Bookshelf
Jul 5, 2017 · The amide local anesthetics including lidocaine, bupivacaine and ropivacaine are commonly used for pain control during minor surgery or invasive procedures such as biopsies, small excisions or dental work.
Topical, Local, and Regional Anesthesia and Anesthetics
Aug 28, 2023 · Two subclasses of local anesthetics categorize according to the location where metabolism occurs. The amino amides such as bupivacaine, ropivacaine, and lidocaine, are hydrolyzed in the liver, whereas plasma cholinesterases metabolize the amino-esters such as procaine, chloroprocaine, and tetracaine.
Basic pharmacology of local anaesthetics - BJA Education
Jul 17, 2019 · Ester and amide local anaesthetic agents differ concerning their metabolism and allergic potential. Esters are hydrolysed rapidly in plasma by pseudocholinesterase to the metabolite para-aminobenzoic acid (PABA), which can cause an allergic reaction.
List of local anesthetics - Wikipedia
This is a list of local anesthetic agents. Not all of these drugs are still used in clinical practice and in research. Some are primarily of historical interest. Drug Other common names ... Amide benzocaine: Anbesol, Orajel Ester - Aminobenzoic Short benzonatate: Tessalon bupivacaine: Marcaine, Sensorcaine, Vivacaine 1957 (Ekenstam)
Local Anesthetics: Review of Pharmacological Considerations
Articaine is classified as an amide local anesthetic because of the linkage between its lipid-soluble ring and terminal amine. Its thiophene ring contains a sulfur atom, which has no immunogenic property, and an ester side chain that renders the compound inactive following hydrolysis.
How Do Amide Local Anesthetics Work? - Uses, Side Effects ... - RxList
Amide local anesthetics are commonly used for pain control during minor surgery. Local anesthesia causes a temporary loss of sensation, including pain, without depressing the consciousness. It acts within nerve fibers to inhibit the rapid inflow of sodium necessary for impulse generation.
Local anesthetics - Journal of Allergy and Clinical Immunology
Local anesthetics may be classified into groups, including esters (aminobenzoate and benzoic acid subtypes), amides, ethers, and ketones. Contact dermatitis is the most common allergic reaction to local anesthetics.
Local Anesthesia: Types, Benefits, and Side Effects - WebMD
Oct 2, 2024 · Local anesthesia relieves pain without the risks and preparation of general anesthesia. You're conscious and alert, and only part of your body is numb. It has other benefits too: An...
What Are Amide Anesthetics? - iCliniq
Nov 17, 2022 · Amide local anesthetics are frequently employed for pain management during minor surgical procedures. Local anesthesia induces a temporary loss of sensation, including pain, without affecting consciousness.