Mayo Clinic researchers have identified interleukin-23 receptor (IL-23R) as a significant biomarker of cellular senescence ...
The body's ability to respond to cellular stress is a critical mechanism for maintaining health. When cells undergo damage or ...
Senescence is the process by which cells irreversibly stop dividing and enter a state of permanent growth arrest without undergoing cell death. Senescence can be induced by unrepaired DNA damage ...
A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science ...
Senescence is the final act in a leaf’s life, when it changes color and falls from the tree. Trees need frosty temperatures ...
LITTLE ROCK - Arkansas' colorful foliage has had an unusually long run this fall. Sadly, it likely won't last much longer, ...
This piece is written in a form of poetry and prose I call a “sonnetina.” It uses the basic form of a music sonata—exposition, development, and recapitulation in which the musical subject matter is ...
另一种药物Fisetin作为一种天然黄酮类化合物,也表现出了广泛的抗衰老潜力。它不仅降低了老年小鼠血浆中IL-17A和其他促炎蛋白的水平,还在雌性小鼠中显著提高了CA13等代谢相关蛋白的表达。这种双向调控的效果表明,Fisetin可能不仅能缓解衰老的 ...
MDM2 turnover and expression of ATRX determine the choice between quiescence and senescence in response to CDK4 inhibition. Oncotarget 10: 8226-43, 2015 Abbas Manji G, Singer S, Koff A, and Schwartz ...