引言衰老是生命过程中不可避免的自然现象，但它并不仅仅是时间的流逝。在人体中，细胞随着分裂次数的增加或遭受外界损伤后，会进入一种称为细胞衰老（Senescence）的状态。这些衰老细胞失去了分裂能力，却并未死亡，而是持续存在于组织中，并通过分泌多种炎性 ...

另一种药物Fisetin作为一种天然黄酮类化合物，也表现出了广泛的抗衰老潜力。它不仅降低了老年小鼠血浆中IL-17A和其他促炎蛋白的水平，还在雌性小鼠中显著提高了CA13等代谢相关蛋白的表达。这种双向调控的效果表明，Fisetin可能不仅能缓解衰老的 ...

Mayo Clinic researchers have identified interleukin-23 receptor (IL-23R) as a significant biomarker of cellular senescence ...

The body's ability to respond to cellular stress is a critical mechanism for maintaining health. When cells undergo damage or ...

A new study led by researchers at The University of Texas Health Science Center at San Antonio (UT Health San Antonio) found ...

Senescence is the final act in a leaf’s life, when it changes color and falls from the tree. Trees need frosty temperatures ...

A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science ...

This piece is written in a form of poetry and prose I call a “sonnetina.” It uses the basic form of a music sonata—exposition, development, and recapitulation in which the musical subject matter is ...

MDM2 turnover and expression of ATRX determine the choice between quiescence and senescence in response to CDK4 inhibition. Oncotarget 10: 8226-43, 2015 Abbas Manji G, Singer S, Koff A, and Schwartz ...