RNA-targeting compounds or small interfering RNAs (siRNAs) offer a potent means for controlling viral infections. An essential prerequisite to their design depends on identifying conserved and ...
N6-methyladenosine (m6A) modification significantly contributes to tumorigenesis and progression by altering RNA secondary structure and influencing RNA-protein binding at the transcriptome level.
In medicine, there are four levels of care: primary, secondary, tertiary, and quaternary. The levels of care refer to the complexity of the medical cases that healthcare providers treat and the skills ...
Simulations were supported by wet lab experiments using nuclear magnetic resonance (NMR), which confirmed that CG-MD can reveal detailed insights into the structure and behavior of RNA nanoparticles.
Deep learning models have emerged as transformative tools by leveraging RNA sequence data. Recent deep learning-based methods integrate multiple sequence alignments (MSAs) and secondary structure ...
RhoFold+ extends its utility beyond 3D structure prediction by accurately predicting RNA secondary structures and Interhelical Angles (IHAs). This expanded functionality highlights its potential ...
Co-infection with HDV and hepatitis B virus is likely underdiagnosed due to challenges in diagnostic test availability and standardization. With new HDV antiviral options, HDV RNA quantification is ...