A systematic exploration revealed that key CD8 + T cells displayed one of the most pronounced signatures of dysregulation, with signs of constant stimulation that lead to an exhausted state, a ...

Exhausted T cells -; which have lost their cancer-fighting oomph -; consume this lactic acid, which further saps their energy, according to new research from the University of Pittsburgh and UPMC ...

Chronic fatigue syndrome creates conditions where pathogen-killing immune T cells become exhausted, according to a new study. Chronic fatigue syndrome creates conditions where pathogen-killing ...

The Houston Texans put together a blunder in every sense on Christmas Day. They were defeated 31-2 by the Baltimore Ravens during the primetime game. They had n ...

By screening FDA-approved drugs, they discovered that miltefosine—a small molecule previously used to treat leishmaniasis—could restore the functionality of exhausted CAR-T cells. Remarkably ...