近日,上海交通大学生物医学工程学院宋萍团队在Journal of the American Chemical Society期刊上发表题为“Random Sanitization in DNA information storage using CRISPR-Cas12a”的最新研究。该研究开发了一种智能核酸探针杂交精准调控与CRISPR-Cas12a反式切割活性的选择性永久擦除方法 ...
In this study, we developed a rapid, sensitive, and visual detection method for MRV and ISKNV using the recombinase polymerase amplification (RPA)−CRISPR/Cas12a system. This method can detect as low ...
This cover highlights the article ZBTB48 is a priming factor regulating B-cell-specific CIITA expression by Grishma Rane, Dennis Kappei and colleagues. The study identifies how ZBTB48, represented as ...
However, while CRISPR sensing seems a promising alternative to established DNA detection techniques, it is not sensitive to epigenetic changes like hypermethylation. In this presentation, we showcase ...
School of Biomedical Engineering, The International Peace Maternity and Child Health Hospital, Zhangjiang Institute for Advanced Study and National Center for Translational Medicine, Shanghai Jiao ...