In a phase II trial, the ROR1-targeting antibody–drug conjugate zilovertamab vedotin led to a complete response in nearly 100% of patients with diffuse large B-cell lymphoma.

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Bristol Myers Squibb announced that the FDA approved nivolumab and hyaluronidase (Opdivo Qvantig) for subcutaneous injection across all currently approved solid tumor indications for intravenous (IV) ...

Major Finding: Tumor-connected neurons promote glioblastoma growth, invasion, and resistance to radiotherapy. Concept: Rabies virus–based retrograde tracing of neurons reveals their integration with ...

Major Finding: Incorporating a modified CD3ε intracellular domain into a chimeric antigen receptor (E-CAR) improves signaling. Concept: E-CARs phase separate and form mature synapses that support ...

After the U.S. Congress pulled funding for a few pediatric cancer programs from the bill passed last week to fund the government through March 14, the Senate voted unanimously to restore a $12.6 ...

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Immune checkpoint blockade therapy, transformative in some cancer types, has remained ineffective for patients with pancreatic cancer. The effects of subpopulations of cancer-associated fibroblasts ...

1Division of Cancer Medicine, University of Texas MD Anderson Cancer Center, Houston, Texas.

Lung cancer significantly impacts mortality, with African Americans (AA) showing higher rates than White Americans (WA). ncRNAs play a crucial role in lung tumorigenesis. To identify ncRNA biomarkers ...

University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States ...

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