引言衰老是生命过程中不可避免的自然现象,但它并不仅仅是时间的流逝。在人体中,细胞随着分裂次数的增加或遭受外界损伤后,会进入一种称为细胞衰老(Senescence)的状态。这些衰老细胞失去了分裂能力,却并未死亡,而是持续存在于组织中,并通过分泌多种炎性 ...
Mayo Clinic researchers have identified interleukin-23 receptor (IL-23R) as a significant biomarker of cellular senescence ...
The exploration of peptides as bioregulatory molecules has gained considerable attention in recent years, with a particular ...
另一种药物Fisetin作为一种天然黄酮类化合物,也表现出了广泛的抗衰老潜力。它不仅降低了老年小鼠血浆中IL-17A和其他促炎蛋白的水平,还在雌性小鼠中显著提高了CA13等代谢相关蛋白的表达。这种双向调控的效果表明,Fisetin可能不仅能缓解衰老的 ...
Chronic inflammation, often driven by persistent immune activation and oxidative stress, exacerbates tissue damage and ...
The body's ability to respond to cellular stress is a critical mechanism for maintaining health. When cells undergo damage or ...
A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and " Aging-US " by Web of ...
LITTLE ROCK - Arkansas' colorful foliage has had an unusually long run this fall. Sadly, it likely won't last much longer, ...
Tesamorelin, a synthetic peptide analog of growth hormone-releasing hormone (GHRH), has recently garnered attention for its unique biochemical properties and intriguing impact on various physiological ...
Senescence is the final act in a leaf’s life, when it changes color and falls from the tree. Trees need frosty temperatures ...
Arkansas' colorful foliage has had an unusually long run this fall, but it likely won't last much longer, said Jaret Rushing, ...