1 Department of Neurobiology, University of Alabama at Birmingham, Birmingham, AL, United States 2 Hugh Kaul Precision Medicine Institute, University of Alabama at Birmingham, Birmingham, AL, United ...

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Through Bayesian analysis of single-cell datasets with variation in nuclear RELA, we predicted that RELA heterogeneity in PDAC cell lines is dependent on F-actin dynamics. RNA-seq analysis identified ...

My research focuses on the cellular and molecular mechanisms underlying synaptic plasticity in the nervous system. Changes at the synaptic level occur both during development and as a result of ...

During macropinocytosis, a protein called actin – which provides structural support to cells – drives the formation of cup-shaped structures from the membrane that surrounds the cell. Several ...

Whereas protein tyrosine and serine/threonine kinase receptors have intrinsic catalytic activity, GPCRs do not have enzymatic activity per se but are linked to Gα proteins, which are GTPases, and ...