Brock Purdy threw for a career-high 377 yards and three touchdowns as the San Francisco 49ers fell to the Detroit Lions 40-34 at Levi's Stadium on Monday Night Football.

Lions 40, 49ers 34, final: The 49ers score a touchdown but can’t recover the onside kick as the Lions hold on for their 14th win of the season. Jared Goff threw for 300 yards, Jahyr Gibbs ran ...

Detroit Lions fans can breath a sigh of relief after Penei Sewell missed just one play and the team otherwise stayed fairly healthy on Monday night against the San Francisco 49ers in the Lions' 40 ...

The Detroit Lions scored on five consecutive drives in the second half to pull away for a 40-34 win over the host San Francisco 49ers on the final "Monday Night Football" matchup of the season.

Watch all of the highlights from the Detroit Lions' 40-34 Week 17 victory over the San Francisco 49ers. Detroit Lions wide receiver Jameson Williams' best plays from his two-touchdown game vs. the San ...

Just when it looked like the Detroit Lions dodged an injury-bullet, they got more bad news. Star defensive tackle Alim McNeill was ruled out with a head injury for the game on Thursday night in ...

The offensive juggernaut that is the Detroit Lions kept rolling along with a 40-34 win against the San Francisco 49ers on Monday in a rematch of the 2023 NFC Championship game. The win moves the ...

The linebacker has now registered at least nine tackles in six games this year, all of which have come in the Lions' last nine contests. On the season, Campbell has now compiled a team-high 125 ...

The Week 18 showdown between the Detroit Lions and the Minnesota Vikings will be a nationally televised affair. NBC has scheduled next week's Detroit vs. Minnesota game in Detroit for Sunday Night ...

The Detroit Lions have been perched atop the NFC for most of the 2024 NFL season. However, one of their top challengers has finally caught up to them. How can the Lions clinch the No. 1 seed?

The Detroit Lions had a tussle as they got ready for the Week 18 main event agains the Minnesota Vikings. Detroit went into San Francisco and outscored the 49ers, 40-34, on Monday night. One of the ...

On Monday night, the Detroit Lions avenged their NFC title loss to the San Francisco 49ers in a thrilling 40-34 victory. It was a meaningless game for the Lions, who will face off against the ...