People inherit two copies of each gene—one from each parent—an evolutionary fail-safe to ensure survival even when one of them doesn't function. For cancer-suppressor genes like BRCA1 ...

By filling the gaps on testing and giving people with harmful mutations better ways to reduce their risk, BRCA1 and BRCA2 testing could become a model for how genetic tests for other cancer risk ...

As the former Hollywood power couple's divorce is settled eight years after it began, we look back at their shared history.

A genetic linkage study is a family-based method used to map a trait to a genomic location by demonstrating co-segregation of the disease with genetic markers of known chromosomal location ...

Studies of Americans and Europeans have pointed to ethnic differences such as a higher prevalence of PGVs in the genes BRCA1 and BRCA2 among Ashkenazi Jewish patients. Brazil has not compiled ...

Dec. 10, 2024 — In a single IV injection, a gene therapy targeting cBIN1 can reverse the effects of heart failure and restore heart function in a large animal model. The therapy increases the ...

Researchers have revealed a new mechanism underlying how spatial distance between specific regions of DNA is linked to bursts of gene activity ... capture the location of DNA, RNA and specific ...

It’s been long known that women with BRCA1 and BRCA2 gene mutations are at higher risk for breast and ovarian cancer. More than 60% of women who inherit a BRCA mutation will develop breast ...