In a deal worth $100 million up front and up to $1.25 billion in milestone payments, Bioarctic AB licensed its pyroglutamate-amyloid-β (pyroglutamate-Aβ) antibody program to Bristol Myers Squibb Co.
Why is age the strongest risk factor for Alzheimer’s disease? In the December 10 Science Signaling ... As SIRT6 peters out, more APP remains to generate Aβ peptides. Indeed, co-first authors Bai and ...
BioArctic's PyroGlu-Aβ antibody program consists of novel antibodies targeting a specific truncated, pyroglutamate modified form of amyloid-beta. Monomers of PyroGlu-Aβ are highly prone to aggregate, ...