Immune checkpoint blockade therapy, transformative in some cancer types, has remained ineffective for patients with pancreatic cancer. The effects of subpopulations of cancer-associated fibroblasts ...

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In a phase II trial, the ROR1-targeting antibody–drug conjugate zilovertamab vedotin led to a complete response in nearly 100% of patients with diffuse large B-cell lymphoma.

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1Department of Experimental Oncology at IEO, European Institute of Oncology IRCCS, Milan, Italy. 11Department of Oncology and Hemato-Oncology, University of Milan, Milan, Italy. 2Department of Human ...

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