For the first time in Nepal, genetic testing, also known as "Gene Sequencing," related to breast cancer (BRCA1 and BRCA2) has ...

People who learn that they carry worrisome BRCA1 mutations need better options to either prevent cancer from developing or intercept it at an early stage. This is particularly crucial for reducing ...

People inherit two copies of each gene—one from each parent—an evolutionary fail-safe to ensure survival even when one of ...

For cancer-suppressor genes like BRCA1, researchers have long hypothesized that a single healthy copy could still guard against tumor development. Yet women with one harmful BRCA1 mutation are far ...

This trial is for women who have changes to the BRCA1 gene but do not have cancer. It is looking at a new way to try and prevent breast cancer. People who have a very strong family history of certain ...

据《美国医学会杂志》发表的研究披露，研究人员开展的一项分析包括了近1万名BRCA1 或 BRCA2基因变异的妇女，这项分析旨在估测有这些基因突变的 ...

Lynparza significantly improves iDFS, DDFS, and OS in BRCA1/2 mutation-positive, HER2-negative high-risk breast cancer patients. The trial's six-year analysis shows consistent benefits across all ...

Adjuvant olaparib continued to show a strong efficacy benefit in patients with BRCA1/2 mutation–positive, HER2-negative ...

Background: Most, if not all, of the cellular functions of the BRCA1 protein are mediated through heterodimeric complexes composed of BRCA1 and a related protein, BARD1. Some breast-cancer ...