In order to understand the role that different genes play in disease pathways, researchers need to be able to modify levels of gene expression. RNA interference (RNAi) technology is well ...

The retina is a dynamic tissue of the eye made up of many different types of cells. Scientists at St. Jude Children's ...

We used this fluorescent indicator of protein folding to evolve proteins that are normally prone to aggregation during expression in ... for (A) gene V (C33T) and (B) bullfrog H-subunit ferritin ...

"pyMS-Vis has allowed us to see histone dynamics that we could not easily see before and opened the door to a more complete ...

mRNA vaccines offer several advantages, including rapid development, scalable production ... The ability to harness the power of mRNA to modulate gene expression and produce desired proteins holds ...

With shallow sampling of the genome-edited libraries, we identify variants with greater than 2-fold improvement in active protein expression. This work demonstrates how rapid genome engineering can be ...

The company is advancing its Phase I/II trial and exploring accelerated approval pathways in the US and Europe.