Nature1 个月
The double (strand break) life of Par-3
In mammalian cells, DNA double-strand breaks (DSBs) are repaired by the non-homologous end-joining (NHEJ) pathway. A key component of this repair mechanism is the DNA binding protein, Ku.
News Medical on MSN1 个月
A novel synthetic lethal target for ATM inhibitors in pancreatic cancer
The underlying mechanism involves BEND4's interaction with Ku80, a key player in the non-homologous end joining (NHEJ) ...
News Medical on MSN1 个月
Epigenetic silencing of BEND4 unveils new path for PDAC treatment
The underlying mechanism involves BEND4's interaction with Ku80, a key player in the non-homologous end joining (NHEJ) ...