An expert spoke with CURE® about the importance of information that can be gained from genetic testing for patients with ...

Real-World Treatment Patterns After Discontinuation of Venetoclax or BTKis in the Frontline Setting Among Older Adults With Chronic Lymphocytic Leukemia Indications for and implications of germline ...

Breast cancer among Emirati patients is characterized by early-onset disease and later stages at presentation. Little is known about the germline genetic variants that may contribute to these ...

This process can help correct genetic disorders by enabling the cell to produce the necessary protein. (Image: National Human Genome Research Institute) Germline gene therapy involves modifying the ...

This study seeks to identify how often we see germline gene mutations (gene mutations people are born with) in men with prostate cancer. This study will evaluate the clinical impact of the genetic ...

In fact, Tavazoie and colleagues had previously demonstrated that various germline alleles of APOE can enhance or suppress melanoma metastasis. To find out whether breast cancer metastasis operates in ...

When mice are engineered to carry a variant of the human PCSK9 gene, they experience higher rates of breast cancer metastasis ...

Patients with germline BRCA mutations who were diagnosed with breast cancer at or before age 40 and who underwent a bilateral risk-reducing mastectomy (RRM) and/or a risk-reducing ...

The findings, published in Cell, provide the first evidence of genetic predisposition to breast ... the 'seeds', that we've ignored the germline—'the soil'. It's now clear that focusing on ...