Scientists mapped how aging alters gene expression across brain cell types in mice, revealing immune activation, neuronal ...

While humans and chimpanzees share many genes, alterations in gene activity may account for distinctive features of the human ...

The integration of external information resources is essential in interpreting intrinsic patterns and relationships in large-scale gene expression data.

2). At the other extreme, the aim is to look at overall patterns of gene expression in order to understand the architecture of genetic regulatory networks, a global approach that could ultimately ...

During the development of the olfactory epithelium (OE), olfactory sensory neurons (OSNs) express only one member of the odorant receptor (OR) gene family, and O ...

This is a valuable polymer model that provides insight into the origin of macromolecular mixed and demixed states within transcription clusters. The well-performed and clearly presented simulations ...

Researchers characterized the gene expression of more than 100,000 individual cells from brains of humans with Alzheimer's disease and compared the patterns to those in individuals with alcohol ...

Our research in this area includes uncovering fundamental mechanisms that regulate how genes are turned on and off in normal cells and how the misregulation of these mechanisms can lead to cancer, as ...

The following is a summary of “Multiomic molecular patterns of lipid dysregulation in a subphenotype of sepsis with higher ...