Cells have extensive sets of intracellular membranes, which together compose the endomembrane system. The endomembrane system was first discovered in the late 1800s when scientist Camillo Golgi ...

We have identified the IRE1/XBP1 branch of the Unfolded Protein Response (UPR) or endoplasmic reticulum (EnR) stress response as a previously unexplored therapeutic vulnerability in MYC-driven breast ...

By studying the role of certain proteins in a cell, researchers have highlighted a key mechanism that can slow aging and ...

The National Institute of Neurological Disorders and Stroke has awarded $2.18 million to two researchers at the University of ...

Due to its dual role in adaptive immune responses, modulation of endoplasmic reticulum aminopeptidase 1 (ERAP1) is considered a potential strategy to both boost cancer immunotherapies or reduce ...

"We showed that these proteins are similar to the highly abundant reticulon proteins, which are known to tubulate endoplasmic reticulum membrane," said Joshi. "We published these findings in ...

Our research group studies the mechanisms of protein trafficking and quality control at the endoplasmic reticulum (ER) in mammalian cells. A major focus of research is on the COPII protein machinery ...

Our research focuses on studies on the molecular structure and mechanism of proteins, recently mostly on the endoplasmic reticulum proteins involved in cellular stress signalling, including in ...

We have a curiosity about endoplasmic reticulum homeostasis, protein aggregates, neural development, and biology of glial cells. We have a passion for excellent level research and high-quality ...

BiPER Therapeutics raises €800,000 in bridge funding to advance its first-in-class BiP-inhibitor for gastrointestinal cancers to clinical trialsNon-dilutive bridge funding marks important milestone ...