Researchers at McMaster University, Canada, have identified a critical biological mechanism involving the protein MANF ...

Our research group studies the mechanisms of protein trafficking and quality control at the endoplasmic reticulum (ER) in mammalian cells. A major focus of research is on the COPII protein machinery ...

We have identified the IRE1/XBP1 branch of the Unfolded Protein Response (UPR) or endoplasmic reticulum (EnR) stress response as a previously unexplored therapeutic vulnerability in MYC-driven breast ...

"We showed that these proteins are similar to the highly abundant reticulon proteins, which are known to tubulate endoplasmic reticulum membrane," said Joshi. "We published these findings in ...

Protein synthesis in eukaryotic cells found in plants, animals, and fungi involves more than just the straightforward ...

Our research focuses on studies on the molecular structure and mechanism of proteins, recently mostly on the endoplasmic reticulum proteins involved in cellular stress signalling, including in ...

BiPER Therapeutics raises €800,000 in bridge funding to advance its first-in-class BiP-inhibitor for gastrointestinal cancers to clinical trialsNon-dilutive bridge funding marks important milestone ...