The study demonstrates how these proteins collaborate in so-called "hubs" to repair DNA damage. This knowledge offers opportunities to improve cancer therapies and other treatments where DNA ...

Normal cells use the nuclear envelope tubules to repair DNA, but cancer cells appear to need them more. To explore the ...

The study demonstrates how these proteins collaborate in so-called "hubs" to repair DNA damage. This knowledge offers opportunities to improve cancer therapies and other treatments where DNA ...

In spite of intensive research, glioblastoma remains one of the most lethal types of brain cancer. Temozolomide (TMZ) is used ...

Mutational signatures etched into the cells' genome by an anti-cancer drug called temozolomide (TMZ) uncover an Achilles' heel for TMZ chemotherapy resistance, according to new research.

Cancer researchers at the University of Chicago ... which is maintained by DNA repair mechanisms that correct any mistakes that occur during DNA replication. Failures in these repair systems ...

A news feature on the research paper "Next-generation cell-penetrating antibodies for tumor targeting and RAD51 inhibition" by Rackear et al. was published in Oncotarget's Volume 15 on November 22, ...

A news feature on the research paper “Next-generation cell-penetrating antibodies for tumor targeting and RAD51 inhibition” ...

Ilya Finkelstein’s research focuses on improving gene editing, understanding DNA repair and finding disease treatments.

Lung cancer occurs when cells in the lungs undergo changes in DNA caused by cigarette smoke ... Initially, the body may be able to repair this damage. However, with repeated exposure, healthy ...