It's an effective tool for killing cancer cells because they are generally much less adept at DNA repair compared to healthy cells. Damaging specific parts of DNA prevents cancer cells from ...

The study demonstrates how these proteins collaborate in so-called "hubs" to repair DNA damage. This knowledge offers opportunities to improve cancer therapies and other treatments where DNA ...

A $4.75m grant will support the development of EIS-12656, which is being studied alone and in combination with PARP ...

In spite of intensive research, glioblastoma remains one of the most lethal types of brain cancer. Temozolomide (TMZ) is used ...

The study demonstrates how these proteins collaborate in so-called "hubs" to repair DNA damage. This knowledge offers opportunities to improve cancer therapies and other treatments where DNA ...

Great white sharks may hold the secrets to curing cancer and other age-related ... The great white's ability to repair its own DNA has evolved in ways ours hasn't. The research was carried out ...

A news feature on the research paper "Next-generation cell-penetrating antibodies for tumor targeting and RAD51 inhibition" by Rackear et al. was published in Oncotarget's Volume 15 on November 22, ...

Mutational signatures etched into the cells' genome by an anti-cancer drug called temozolomide (TMZ) uncover an Achilles' heel for TMZ chemotherapy resistance, according to new research.

Ilya Finkelstein’s research focuses on improving gene editing, understanding DNA repair and finding disease treatments.