More information: Kim L. de Luca et al, Genome-wide profiling of DNA repair proteins in single cells, Nature Communications (2024). DOI: 10.1038/s41467-024-54159-4 Provided by Hubrecht Institute ...
Cells use repair systems to fix this damage, with specialized proteins locating and binding to the damaged regions. Zooming in on individual cells The body has various mechanisms to repair DNA ...
Her research team is focused on two DNA repair proteins—SWSAP1 and SWS1, known together as the Shu complex. Using a million-dollar advanced research instrument called a C-trap, which uses lasers ...
New research from the Kind Group sheds light on how cells repair damaged DNA. For the first time, the team has mapped the activity of repair proteins in individual human cells. The study demonstrates ...
Mutational signatures etched into the cells' genome by an anti-cancer drug called temozolomide (TMZ) uncover an Achilles' heel for TMZ chemotherapy resistance, according to new research.