DNA damage and repair refers to the creation and correction of DNA lesions that threaten genome integrity. Because DNA replication errors or environmental agents that damage DNA can introduce ...
Various intermediates in the base excision repair (BER) of a DNA base lesion (Adduct, ) are illustrated, including: an uncleaved AP site (AP site, ), a 5′-uncleaved AP site (Nicked DNA with dRP ...
This knowledge offers opportunities to improve cancer therapies and other treatments where DNA repair is essential. The researchers published their findings in Nature Communications on November 21.
The study, recently published online in the journal Aging Cell ... "Our findings highlight the critical role DNA damage repair plays in maintaining retina health for good vision," said co ...