There is significant crosstalk between DNA damage response (DDR) pathways and innate immune pathways. Both the individual pathways and their interactions are key areas of interest for the ...

As previously mentioned, one important DNA damage response (DDR) is triggered by exposure to UV light. Of the three categories of solar UV radiation, only UV-A and UV-B are able to penetrate Earth ...

▎药明康德内容团队编辑（来源：北京大学）DNA损伤修复在维持基因组稳定性中发挥关键作用，其相关基因的突变可能危害基因组完整性，并增加癌症发生的风险。顺铂（Cisplatin）和电离辐射（IR）等DNA损伤药物被广泛用于肿瘤治疗，但临床治疗中不断发现病 ...

Sixty years ago, we nearly wiped out bed bugs—but they’ve been making a steady comeback, and they’re stronger than ever.

the authors applied CRISPRmap to investigate the functional consequences of 292 mutations in 27 genes critical for the DNA ...

The private placement is subject to the final acceptance of the TSXV and all securities issuable in connection with the private placement are subject to a hold period of four months plus one day from ...

The primary end point was objective response rate, and secondary end points included ... histologic diagnosis of malignancy and known somatic mutation of component of DNA damage repair pathway. Both ...

The input of the DeepTXsolver is the parameters of the mechanism model, and the output is the corresponding stationary distribution solution of the model. The input to the DeepTXinferrer is the ...

In September, Rakovina initiated a collaboration with Variational AI to use their Enki™ platform to discover novel kinase inhibitors. This partnership is focused on developing new therapies that could ...