The Michigan State Spartans travel to take on the Ohio State Buckeyes in the marquee matchup of Friday night. Who has the advantage in that contest? Meanwhile, in the Big East, the Marquette Golden Eagles host the Crighton Bluejays.

The last meeting came in 2014, in a game that Oregon won by seven points. Illinois has had a good start to the season and is probably only regretting a loss at Northwestern that came during a bad night. The Ducks have started strongly as well, with their lone loss coming by just two points to UCLA.

Predictions, picks and odds as Clemson faces Cal on Saturday in ACC play. Plus, injury updates and latest news.