Moreover, as the gene sequence is known, it can be used time and again. “Knowing that your antibody is going to behave the same way years down the line, gives you peace of mind,” Solache adds.

“Integrated with single cell sequencing technology, the target antibody sequences can be easily obtained. This reduces the cycle of the whole process, from defining the target to generating ...

The sequence homology is over 95%; PTM and aggregation prediction reports are also available 100% success rate As quick as 3–4 weeks to offer required humanized antibodies Affinity evaluated by ...

The process is followed by computationally guided mutagenesis or evolution of the antibody sequence (hit to lead, or H2L, optimisation) to improve the binding and other properties. Although the ...

Recombinant antibody technology has helped address many problems associated with hybridoma platforms, opening the door to a ...

Monoclonal antibodies are considered the most rapidly growing class of therapeutics. Critical quality attributes such as sequence assessment, charge and size variants must be thoroughly monitored ...

The researchers created input data for the deep-learning model using sequences of known antigen binders. This method ...

The exact values can be found in Dataset S2. Shown are SDS-PAGE time course (A, B) and LC-MS analyses (C) of αHER2 (human epidermal growth factor receptor 2) antibody conjugations. The αHER2 heavy (HC ...