They focused on a protein called BACE1 ... To quantify the amount of amyloid plaque, the researchers used a combination of molecular imaging techniques and biochemical assays.
A study by the team of Prof. Kristel Sleegers (VIB-UAntwerp), published in Acta Neuropathologica, has offered new insights into the genetic factors that drive Alzheimer's disease. Using samples ...
A new gene editing tool that helps cellular machinery skip parts of genes responsible for diseases has been applied to reduce the formation of amyloid-beta plaque precursors in a mouse model of ...
The researchers targeted a specific exon coding for an amino acid sequence within a protein that gets cleaved to form amyloid-beta, which accumulates to form plaques on neurons in the brain as the ...
Immune cells in the brain called microglia can partially break down large amyloid plaques characteristic of Alzheimer's disease by latching on to them, forming a sort of external stomach and ...
Alzheimer’s disease may cause degeneration of neurons in the brain through amyloid plaques, neurofibrillary tangles, inflammation, and brain atrophy. The condition may affect different parts of ...